Method and apparatus for loading a guidewire into a connector with a valve

ABSTRACT

A guidewire introducer for loading a guidewire into a connector with a valve. The guidewire introducer having a proximal end, a distal end and a slit along a length of the guidewire introducer between the proximal end and the distal end. The guidewire introducer is sufficiently rigid to create a passageway to allow the guidewire introducer to get past the valve without collapsing and wherein the slit closes when the guidewire introducer is inserted into the valve.

CROSS-REFERENCE TO RELATED PATENT APPLICATIONS

This application is a divisional of U.S. application Ser. No.15/429,985, filed Feb. 10, 2017, titled METHOD AND APPARATUS FOR LOADINGA GUIDEWIRE INTO A CONNECTOR WITH A VALVE, which is incorporated hereinby reference in its entirety.

FIELD OF THE INVENTION

The present invention relates generally to the field of catheter systemsfor performing therapeutic procedures and, in particular, to a methodand apparatus for loading a guidewire into a connector with a valve.

BACKGROUND OF THE INVENTION

Catheters may be used for many medical procedures, including inserting aguidewire, delivering a stent and delivering and inflating a balloon.Catheterization procedures are commonly performed for diagnosis andtreatment of diseases of the heart and vascular systems. Thecatheterization procedure is generally initiated by inserting aguidewire into a blood vessel in the patient's body. The guidewire isthen advanced to the desired location, most commonly in one of the heartvessels or elsewhere in the vascular system. At this point, a catheteris slid over the guidewire into the blood vessel and/or heart. In someprocedures, the catheter is a balloon catheter or stent delivery systemthat when deployed at the site of the lesion allows for increased bloodflow through the portion of the coronary artery that is affected by thelesion.

For manual insertion of a guidewire, the physician applies torque andaxial push force on the proximal end of a guidewire to effect tipdirection and axial advancement at the distal end. Robotic catheterprocedure systems have been developed that may be used to aid aphysician in performing a catheterization procedure such as apercutaneous coronary intervention (PCI). The physician uses a roboticsystem to precisely steer a coronary guidewire, balloon catheter orstent delivery system in order to, for example, widen an obstructedartery. While observing the coronary anatomy using fluoroscopy, thephysician manipulates a device, for example a guidewire, in order todirect the device into the appropriate vessels toward the lesion. Arobotic catheter procedure system includes drive mechanisms to drivevarious elongated medical devices (e.g., guidewire, guide catheter,working catheter) used in catheterization procedures to provide linearand rotational movement of the elongated medical device.

During one type of catheter procedure, a guide catheter is inserted intoeither a patient's femoral or radial artery through an introducer andthe guide catheter is positioned proximate the coronary ostium of thepatient's heart. During the procedure, the guide catheter is used toguide other elongated medical devices such as a guidewire or a ballooncatheter into a patient. Typically, the end of the guide catheter notinserted into the patient is connected to a connector, such as ay-connector, with a valve (e.g., a hemostasis valve) to allowintroduction of an elongated medical device and a contrast agent ormedicine into a lumen of the guide catheter. For example, a first leg ofthe y-connector may be configured to receive a guidewire or otherelongated medical device and a second leg of the y-connector may beconfigured to allow introduction of a contrast agent or medicine. Thefirst leg of a y-connector may also include a valve that permitsinsertion or removal of the guidewire or other elongated medical devicebut prohibits fluids from exiting the first leg. A guidewire may have aflexible or floppy end which can be difficult to insert past the valvein the connector. It would be desirable to provide an apparatus andmethod for loading a guidewire into a connector that allows the flexibleend of the guidewire to advance past a valve in the connector and thatallows the guidewire introducer to be removed proximate to the connectorwithout having to thread the guidewire introducer off the entire lengthof the guidewire to the proximal end of the guidewire.

SUMMARY OF THE INVENTION

In accordance with an embodiment, a method for loading a guidewire intoa connector using a guidewire introducer includes inserting a guidewireintroducer into a proximal end of a connector, the guidewire introducerhaving a proximal end, a distal end and a slit along the length of theguidewire introducer between the proximal end and the distal end,advancing the guidewire introducer past a valve in the proximal end ofthe connector, inserting a distal end of a guidewire into the proximalend of the guidewire introducer, advancing the guidewire through theguidewire introducer and through the connector, removing the guidewireintroducer from the connector so that the distal end of the guidewireintroducer is outside of the connector and proximate to the proximal endof the connector and removing the guidewire introducer from theguidewire using the slit in the guidewire introducer.

In accordance with another embodiment, a guidewire introducer forloading a guidewire into a connector with a valve includes a body havinga length, a proximal end and a distal end, a slit having a spiralconfiguration along the length between the proximal end and the distalend and a tapered portion at the proximal end.

In accordance with another embodiment, a guidewire introducer forloading a guidewire into a connector with a valve includes a body havinga length, a proximal end and a distal end, a slit having a zig-zagconfiguration along the length between the proximal end and the distalend and a tapered portion at the proximal end.

BRIEF DESCRIPTION OF THE DRAWINGS

This application will become more fully understood from the followingdetailed description, taken in conjunction with the accompanyingfigures, wherein like reference numerals refer to like elements inwhich:

FIG. 1 is a perspective view of an exemplary catheter procedure systemin accordance with an embodiment;

FIG. 2 is a perspective view of an exemplary y-connector in accordancewith an embodiment;

FIG. 3 is a perspective view of a y-connector and guide catheter inaccordance with an embodiment;

FIG. 4 is a perspective view of a guidewire introducer with a lengthwiseslit in accordance with an embodiment;

FIG. 5 is a perspective view of a guidewire introducer with a spiralslit in accordance with an embodiment;

FIG. 6 is a perspective view of a guidewire introducer with a spiralslit in accordance with an embodiment;

FIG. 7 illustrates a method for loading a guidewire into a connector inaccordance with an embodiment;

FIG. 8 is a perspective view of a guidewire introducer positioned withina y-connector in accordance with an embodiment;

FIG. 9 is a perspective view of a y-connector, guide catheter; guidewireintroducer and guidewire in accordance with an embodiment;

FIG. 10 is a perspective view of a guidewire positioned within aguidewire introducer in accordance with an embodiment;

FIG. 11 is a perspective view of a y-connector, guide catheter,guidewire introducer and guidewire in accordance with an embodiment; and

FIG. 12 is a perspective view of a y-connector, guide catheter andguidewire in accordance with an embodiment.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

FIG. 1 is a perspective view of an exemplary catheter procedure systemin accordance with an embodiment. In FIG. 1, a catheter procedure system100 may be used to perform catheter based medical procedures (e.g., apercutaneous intervention procedure). Catheter based medical proceduresmay include diagnostic catheterization procedures during which one ormore catheters are used to aid in the diagnosis of a patient's disease.For example, during one embodiment of a catheter based diagnosticprocedure, a contrast media is injected onto one or more coronaryarteries through a catheter and an image of the patient's heart istaken. Catheter based medical procedures may also include catheter basedtherapeutic procedures (e.g., angioplasty, stent placement, treatment ofperipheral vascular disease, etc.) during which a catheter is used totreat a disease. It should be noted, however, that one skilled in theart would recognize that certain specific percutaneous interventiondevices or components (e.g., type of guidewire, type of catheter, etc.)will be selected based on the type of procedure that is to be performed.Catheter procedure system 100 is capable of performing any number ofcatheter based medical procedures with minor adjustments to accommodatethe specific percutaneous intervention devices to be used in theprocedure. In particular, while the embodiments of catheter proceduresystem 100 described herein are explained primarily in relation to thetreatment of coronary disease, catheter procedure system 100 may be usedto diagnose and/or treat any type of disease or condition amenable todiagnosis and/or treatment via a catheter based procedure.

Catheter procedure system 100 includes lab unit 106 and workstation 116.Catheter procedure system 100 includes a robotic catheter system, shownas bedside system 110, located within lab unit 106 adjacent a patient102. Patient 102 is supported on a table 108. Generally, bedside system110 may be equipped with the appropriate percutaneous interventiondevices or other components (e.g., guidewires, guide catheters, workingcatheters such as balloon catheters and stent delivery systems, contrastmedia, medicine, diagnostic catheters, etc.) to allow the user toperform a catheter based medical procedure via a robotic system byoperating various controls such as the controls located at workstation116. Bedside system 110 may include any number and/or combination ofcomponents to provide bedside system 110 with the functionalitydescribed herein. Bedside system 110 includes, among other elements, adrive assembly 114 (e.g., that may contain a sterile, disposableportion) supported by a robotic arm 112 which may be used toautomatically advance a guidewire or working catheter into a guidecatheter seated in an artery of the patient 102.

Bedside system 110 is in communication with workstation 116, allowingsignals generated by the user inputs of workstation 116 to betransmitted to bedside system 110 to control the various functions ofbedside system 110. Bedside system 110 may also provide feedback signals(e.g., operating conditions, warning signals, error codes, etc.) toworkstation 116. Bedside system 110 may be connected to workstation 116via a communication link that may be a wireless connection, cableconnections, or any other means capable of allowing communication tooccur between workstation 116 and bedside system 110.

Workstation 116 includes a user interface 126 configured to receive userinputs to operate various components or systems of catheter proceduresystem 100. User interface 126 includes controls 118 that allow the userto control bedside system 110 to perform a catheter based medicalprocedure. For example, controls 118 may be configured to cause bedsidesystem 110 to perform various tasks using the various percutaneousintervention devices with which bedside system 110 may be equipped(e.g., to advance, retract, or rotate a guidewire, advance, retract orrotate a working catheter, advance, retract, or rotate a guide catheter,inflate or deflate a balloon located on a catheter, position and/ordeploy a stent, inject contrast media into a catheter, inject medicineinto a catheter, or to perform any other function that may be performedas part of a catheter based medical procedure). Drive assembly 114includes various drive mechanisms to cause movement (e.g., axial androtational movement) of the components of the bedside system 110including the percutaneous devices.

In one embodiment, controls 118 include a touch screen 124, one or morejoysticks 128 and buttons 130, 132. The joystick 128 may be configuredto advance, retract, or rotate various components and percutaneousdevices such as, for example, a guidewire, a guide catheter or a workingcatheter. Buttons 130, 132 may include, for example, an emergency stopbutton and a multiplier button. When an emergency stop button is pusheda relay is triggered to cut the power supply to bedside system 110.Multiplier button acts to increase or decrease the speed at which theassociated component is moved in response to a manipulation of controls118. In one embodiment, controls 118 may include one or more controls oricons (not shown) displayed on touch screen 124, that, when activated,causes operation of a component of the catheter procedure system 100.Controls 118 may also include a balloon or stent control that isconfigured to inflate or deflate a balloon and/or a stent. Each of thecontrols may include one or more buttons, joysticks, touch screen, etc.that may be desirable to control the particular component to which thecontrol is dedicated. In addition, touch screen 124 may display one ormore icons (not shown) related to various portions of controls 118 or tovarious components of catheter procedure system 100.

User interface 126 may include a first monitor or display 120 and asecond monitor or display 122. First monitor 120 and second monitor 122may be configured to display information or patient specific data to theuser located at workstation 116. For example, first monitor 120 andsecond monitor 122 may be configured to display image data (e.g., x-rayimages, MRI images, CT images, ultrasound images, etc.), hemodynamicdata (e.g., blood pressure, heart rate, etc.), patient recordinformation (e.g., medical history, age, weight, etc.). In addition,first monitor 120 and second monitor 122 may be configured to displayprocedure specific information (e.g., duration of procedure, catheter orguidewire position, volume of medicine or contrast agent delivered,etc.). Monitor 120 and monitor 122 may be configured to displayinformation regarding the position the guide catheter. Further, monitor120 and monitor 122 may be configured to display information to providethe functionalities associated with a controller of the system (e.g.,located in workstation 116 or in communication with workstation 116). Inanother embodiment, user interface 126 includes a single screen ofsufficient size to display one or more of the display components and/ortouch screen components discussed herein.

Catheter procedure system 100 also includes an imaging system 104located within lab unit 106. Imaging system 104 may be any medicalimaging system that may be used in conjunction with a catheter basedmedical procedure (e.g., non-digital x-ray, digital x-ray, CT, MRI,ultrasound, etc.). In an exemplary embodiment, imaging system 104 is adigital x-ray imaging device that is in communication with workstation116. In one embodiment, imaging system 104 may include a C-arm (notshown) that allows imaging system 104 to partially or completely rotatearound patient 102 in order to obtain images at different angularpositions relative to patient 102 (e.g., sagittal views, caudal views,anterior-posterior views, etc.).

Imaging system 104 may be configured to take x-ray images of theappropriate area of patient 102 during a particular procedure. Forexample, imaging system 104 may be configured to take one or more x-rayimages of the heart to diagnose a heart condition. Imaging system 104may also be configured to take one or more x-ray images during acatheter based medical procedure (e.g., real time images) to assist theuser of workstation 116 to properly position a guidewire, guidecatheter, stent, etc. during the procedure. The image or images may bedisplayed on first monitor 120 and/or second monitor 122. In particular,images may be displayed on first monitor 120 and/or second monitor 122to allow the user to, for example, accurately move a guide catheter intothe proper position.

As used herein, the direction distal is the direction toward the patientand the direction proximal is the direction away from the patient. Theterms up and upper refer to the general direction away from thedirection of gravity and the terms bottom, lower and down refer to thegeneral direction of gravity.

Bedside system 110 of catheter procedure system 100 may include aconnector that may be in communication with a guide catheter, guidewireand a working catheter. The connector includes a valve, e.g., ahemostasis valve. The following description discusses embodiments withrespect to a y-connector, however, it should be understood that theconnector may be any other type of connector including a valve such as astraight connector (e.g., a connector with a single leg). FIG. 2 is aperspective view of an exemplary y-connector in accordance with anembodiment. In one embodiment, y-connector 200 is a hemostasis valve.Y-connector 200 includes a valve body with a first leg 202 having aproximal end 204, a distal end 206 and a lumen extending between theproximal end 204 and the distal end 206. A proximal port or opening 205is adjacent to the proximal end 204 and a distal port or opening 207 isadjacent the distal end 206. The first leg 202 defines a longitudinalaxis 210 extending from the proximal end 204 of the first leg 202 to thedistal end 206 of the first leg 202. The y-connector 200 also includes asecond leg 208 that is angled away from the longitudinal axis 210defined by the first leg 202. The second leg 208 includes an internallumen and is in fluid communication with the lumen of the first leg 202.

The first leg 202 of y-connector 200 includes a valve adjacent to theproximal end 204 that permits insertion and removal of a percutaneousdevice such as a guidewire or working catheter into the y-connector 200and prohibits fluids from exiting the proximal end 204 of the first leg202. In one embodiment, the valve may be a bleed-back valve that may beused to reduce the blood that may be lost during an interventionalprocedure. The bleed-back valve acts to allow an elongated device suchas a guidewire to extend therethrough but minimizes blood loss throughthe valve. In another embodiment, the proximal end 204 of the first leg202 may include a Tuohy Borst adapter. Tuohy Borst adapters are known inthe art and operate to adjust the size of the opening 205 in theproximal end 204 of the first leg 202 of the y-connector 200 to minimizethe risk that fluids may exit the proximal end 204 of the first leg 202.For example, a Tuohy Borst adapter may be used to adjust the size of theopening to zero to stop flow of fluid or may be used to adjust toopening to hold onto or fixate an elongated medical device (e.g., aguidewire) that is passing through it. In another embodiment, theconnector (e.g., y-connector 200) may include both a bleed-back valveand a Tuohy Borst adapter. Other types of adapters known in the art maybe used with the y-connector 200 to adjust the size of the opening 205in the proximal end 204 of the first leg 202.

The distal end 206 of the first leg 202 may be connected to a guidecatheter as shown in FIG. 3. In FIG. 3, a guide catheter 212 has aproximal end 214 and a distal end 216. The proximal end 214 of the guidecatheter 212 is attached to the distal end 206 of the first leg 202 ofthe y-connector 200. In one embodiment, the distal end 206 of the firstleg 202 is attached to the proximal end 214 of the guide catheter 212such that the central lumen of y-connector 200 is in fluid communicationwith the central lumen of the guide catheter 212. The second leg 208 ofthe y-connector 200 provides a port for the introduction of fluids(e.g., contrast media, medicine, etc.) into the lumen of the guidecatheter 212. An elongated medical device such as a guidewire or workingcatheter may be advanced into the guide catheter 212 through they-connector 200. For example, a guidewire (not shown) may be insertedinto the proximal end 204 of the first leg 202 and through the first leg202 of the y-connector 200 into the lumen of the guide catheter 212.

A guidewire introducer may be used to facilitate insertion of aguidewire into the y-connector and past the valve in the proximal end ofthe first leg of the y-connector. FIG. 4 is a perspective view of aguidewire introducer with a lengthwise slit in accordance with anembodiment. The guidewire introducer 220 includes a proximal end 222 anda distal end 224. The proximal end 222 includes a tapered portion 228 toallow insertion of a guidewire into the proximal end 222 of theguidewire introducer 220. The guidewire introducer 220 also includes aslit 226 that is continuous along the entire length of the guidewireintroducer 220 between the proximal end 222 and the distal end 224. Inone embodiment, the guidewire introducer 220 has sufficient rigidity toallow the guidewire introducer 220 to go through the valve and create apassageway to allow the guidewire introducer to go through the valve andcreate a passageway to allow a guidewire to get past the valve withoutcollapsing or damaging the distal tip of the guidewire. In oneembodiment, the slit 226 may be configured to close when it is insertedin the valve in a manner such as a spring pin or to close and overlapitself in a manner such as a coiled spring pin and then open again whenremoved from the valve. For example, the compliance of the material usedto construct the guidewire introducer 220 may be selected to allow theslit 226 to close or to overlap itself when the guidewire introducer 220is inserted into the valve and to allow the slit 226 to spring open whenthe guidewire introducer 220 is removed from the valve. The slit 226 mayhave a width that is similar to the width of the guidewire, smaller thanthe guidewire or larger than the guidewire.

As discussed further below, the slit 226 may be used to remove theguidewire introducer 220 from over a guidewire without requiring theguidewire introducer 220 be slid or threaded over the length of theguidewire to a proximal end of the guidewire. In an embodiment, theproximal end 222 of the guidewire introducer 220 may include a tab (notshown) that may be used to remove (e.g., pull the introducer off of aguidewire). The tab (not shown) may be positioned on the tapered portion228 opposite the slit 226. In another embodiment, the guidewireintroducer with slit includes a spiral slit along the length of theguidewire introducer as shown in FIGS. 5 and 6. In FIG. 5, the guidewireintroducer 250 includes a proximal end 252 and a distal end 254. Theproximal end 252 includes a tapered portion 258 to allow insertion of aguidewire into the proximal end 252. A slit 256 is provided along thelength of the guidewire introducer 250 between the proximal end 252 andthe distal end 254. The slit 256 is in a spiral configuration along thelength of the guidewire introducer 250. In FIG. 6, an alternative spiralconfiguration of a slit 260 along the length of the guidewire introducer250 is shown. In another embodiment, the slit along the length of theguidewire introducer between the proximal end and the distal end may bea zig-zag configuration. In yet another embodiment, the slit may bestraight along a portion of the length of the guidewire introducer(e.g., proximate the proximal end) and then a spiral or zig-zagconfiguration along the remaining portion of the length of the guidewireintroducer towards the distal end.

The following description of FIGS. 7-12 discusses embodiments withrespect to a y-connector, however, it should be understood that theconnector may be any other type of connector including a valve (e.g., ahemostasis valve) such as a straight connector (e.g., a connector with asingle leg). FIG. 7 illustrates a method for loading a guidewire into aconnector in accordance with an embodiment. At block 302, a guidewireintroducer with a slit is inserted into the proximal end of the firstleg of the y-connector. At block 304, the guidewire introducer isadvanced past the valve in the proximal end of the first leg of they-connector and towards the distal end of the first leg of they-connector. FIG. 8 is a perspective view of a guidewire introducerpositioned within a y-connector in accordance with an embodiment. InFIG. 8, the guidewire introducer 220 is shown after insertion into theproximal end 204 of first leg 202 of the y-connector 200. The guidewireintroducer 220 is advanced through the first leg 202 past the valve inthe proximal end 204 and towards the distal end 206 of the first leg202.

Returning to FIG. 7, at block 306, a distal end of a guidewire isinserted into the proximal end of the guidewire introducer. FIG. 9 is aperspective view of a y-connector, guide catheter; guidewire introducerand guidewire in accordance with an embodiment. In FIG. 9, a guidewire230 incudes a distal end 232 that may be inserted into the proximal end222 of the guidewire introducer 220. In one embodiment, the distal end232 of the guidewire may be flexible or bendable to put a curve at thetip. In another embodiment, the distal end of the guidewire may bepre-shaped with a curve. Returning to FIG. 7, at block 308, the distalend of the guidewire is advanced through the guidewire introducer andy-connector into the guide catheter. FIG. 10 is a perspective view of aguidewire positioned within a guidewire introducer in accordance with anembodiment. In FIG. 10, the guidewire 230 is shown after the distal endhas been inserted into the guidewire introducer 220 and through they-connector 200 into the guide catheter 212. The guidewire introducer220 facilitates advancement of the distal end 232 (shown in FIG. 9) ofthe guidewire 230 past the valve in the proximal end 204 of the firstleg 202 of the y-connector 200.

Returning to FIG. 7, at block 310 once the guidewire is advanced intothe guide catheter, the guidewire introducer is removed from they-connector over the guidewire until the distal end of the guidewireintroducer is outside of the y-connector and proximate to the proximalend of the y-connector. FIG. 11 is a perspective view of a y-connector,guide catheter, guidewire introducer and guidewire in accordance with anembodiment. In FIG. 11, the guidewire introducer 220 is shown afterremoval from the y-connector 200. The guidewire introducer 220 ispositioned over the guidewire and the distal end 224 of the guidewireintroducer 220 is proximate to the proximal end 204 of the y-connector200. Returning to FIG. 7, at block 312, the guidewire introducer isremoved from the guidewire via the lengthwise slit 226 (shown in FIG.11) in the guidewire introducer. FIG. 12 is a perspective view of ay-connector, guide catheter and guidewire in accordance with anembodiment. In FIG. 12, the guidewire introducer has been removed andthe guidewire 230 is positioned in the y-connector 200 and guidecatheter 212. Referring to FIG. 4 and FIG. 11 The guidewire introducerincludes a first tapered portion proximate the proximal end 222 and asecond tapered portion proximate the distal end 224, the diameter of thefirst tapered portion decreasing from the proximal end 222 toward thedistal end 224 and the dimeter of the second tapered portion decreasingfrom a region proximal the distal end 224 of the second tapered portiontoward the distal end 224 of the second tapered portion.

This written description used examples to disclose the invention,including the best mode, and also to enable any person skilled in theart to make and use the invention. The patentable scope of the inventionis defined by the claims, and may include other examples that occur tothose skilled in the art. Such other examples are intended to be withinthe scope of the claims if they have structural elements that do notdiffer from the literal language of the claims, or if they includeequivalent structural elements with insubstantial differences from theliteral language of the claims. The order and sequence of any process ormethod steps may be varied or re-sequenced according to alternativeembodiments.

Many other changes and modifications may be made to the presentinvention without departing from the spirit thereof. The scope of theseand other changes will become apparent from the appended claims.

What is claimed is:
 1. A guidewire introducer for loading a guidewireinto a connector with a valve, the guidewire introducer comprising: aguidewire introducer having a proximal end, a distal end and a slitalong an entire length of the guidewire introducer between the proximalend and the distal end; the guidewire introducer being sufficientlyrigid to create a passageway to allow the guidewire introducer to getpast the valve without collapsing and wherein the slit closes when theguidewire introducer is inserted into the valve; and the guidewireintroducer being removable from the guidewire using the slit in theguidewire introducer without requiring the guidewire introducer to beslid or threaded over a length of the guidewire to a proximal end of theguidewire.
 2. The guidewire introducer of claim 1, wherein the proximalend of the guidewire introducer is tapered.
 3. The guidewire introducerof claim 1, wherein the connector includes a distal end and the distalend is connected to a guide catheter.
 4. The guidewire introducer ofclaim 1, wherein advancing the guidewire through the guidewireintroducer and through the connector further comprises advancing theguidewire into a guide catheter.
 5. The guidewire introducer of claim 1,wherein the distal end of the guidewire is flexible.
 6. The guidewireintroducer of claim 1, wherein the valve in the connector is selectedfrom a group of valves consisting of a hemostasis valve, a bleed-backvalve and a portion of a Tuohy Borst adapter.
 7. The guidewireintroducer of claim 1, wherein the slit has a spiral configuration alongthe length of the guidewire introducer.
 8. The guidewire introducer ofclaim 1, wherein at least a portion of the slit springs open when theguidewire introducer is removed from the valve.
 9. The guidewireintroducer of claim 1, wherein the guidewire introducer is formed of amaterial having sufficient compliance to allow the slit to close whenthe guidewire introducer is inserted into the valve.
 10. The guidewireintroducer of claim 1, the slit overlaps itself in response to insertionof the guidewire introducer into the valve.
 11. The guidewire introducerof claim 1, wherein the guidewire introducer includes a first taperedportion proximate the proximal end and a second tapered portionproximate the distal end, the diameter of the first tapered portiondecreasing from the proximal end toward the distal end and the diameterof the second tapered portion decreasing from the proximal distal end ofthe second tapered portion toward the distal end of the second taperedportion.
 12. The guidewire introducer of claim 1, wherein portions ofthe slit are open, with opposing edges of the portions of the slit beingspaced apart and out of mutual contact, prior to the inserting of theguidewire introducer into a proximal end of the connector and whereinpositioning of the guidewire introducer into the valve results in theportions of the slit closing.
 13. The guidewire introducer of claim 12,wherein the slit closes by overlapping itself in response to insertionof the guidewire introducer into the valve.
 14. The guidewire introducerof claim 12, wherein the opposing edges of the portions of the slit arespaced apart by width greater than or equal to a width of the guidewireprior to inserting the guidewire introducer into the proximal end of theconnector.
 15. The guidewire introducer of claim 12, wherein the valveconstricts the portions of the slit to close the slit duringintroduction of the portions of the slit into the valve.
 16. Theguidewire introducer of claim 12, wherein the slit closes by overlappingitself in response to insertion of the guidewire introducer into thevalve.
 17. A guidewire introducer for loading a guidewire into aconnector with a valve, the guidewire introducer comprising: a guidewireintroducer having a proximal end, a distal end and a slit along a lengthof the guidewire introducer between the proximal end and the distal end;wherein the guidewire introducer is sufficiently rigid to create apassageway to allow the guidewire introducer to get past the valvewithout collapsing and wherein the slit closes when the guidewireintroducer is inserted into the valve.
 18. The guidewire introducer ofclaim 17, wherein the guidewire introducer is formed of a materialhaving sufficient compliance to allow at least a portion of the slit toclose when the guidewire introducer is inserted into the valve and tospring open when the guidewire introducer is removed from the valve. 19.The guidewire introducer of claim 18, wherein when the slit is openopposing edges of the portions of the slit are spaced apart by a widthsufficient to allow a guidewire to be inserted into the passagewaythrough the slit.
 20. The guidewire introducer of claim 19, wherein theslit extends along an entire length of the guidewire introducer andwherein the guidewire introducer may be removed from the guidewire usingthe slit without requiring the guidewire introducer to be slid orthreaded over the length of the guidewire to a proximal end of theguidewire.